Open AccessPhenotypic and functional evaluation of CD3+CD4-CD8- T cells in human CD8 immunodeficiency
Author(s) -
Iván Bernardo,
Esther Mancebo,
Ignacio Aguiló,
Alberto Anel,
Luis M. Allende,
Juan-Manuel Guerra-Vales,
Jesús Ruíz-Contreras,
Antonio Serrano,
Paloma Talayero,
Oscar de la Calle,
Cecilia González-Santesteban,
Estela Paz-Artal
Publication year - 2011
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2011.041301
Subject(s) - cytotoxic t cell , cd8 , biology , population , microbiology and biotechnology , t cell , interleukin 21 , immunology , antigen , immune system , in vitro , genetics , medicine , environmental health
Human CD8 immunodeficiency is characterized by undetectable CD8(+) lymphocytes and an increased population of CD4(-)CD8(-) (double negative) T lymphocytes.