Open AccessPrimary plasma cell leukemia and autologous stem cell transplantation
Author(s) -
Mary Drake,
Simona Iacobelli,
Anja van Biezen,
Curly Morris,
Jane F. Apperley,
Dietger Niederwieser,
Bo Björkstrand,
Gösta Gahrton
Publication year - 2010
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2009.013334
Subject(s) - plasma cell leukemia , stem cell , transplantation , leukemia , medicine , primary (astronomy) , cancer research , oncology , immunology , biology , bone marrow , microbiology and biotechnology , physics , astronomy
Primary plasma cell leukemia is a rare disorder accounting for less than 5% of malignant plasma cell diseases. It has a poor prognosis compared to multiple myeloma, with a median survival of 8-12 months. The results of conventional therapy are disappointing though autologous stem cell transplantation may improve survival.