Open AccessPathobiological considerations relating to the treatment of intraductal carcinoma (ductal carcinoma in situ) of the breast
Author(s) -
Fisher Edwin R.
Publication year - 1997
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/canjclin.47.1.52
Subject(s) - ductal carcinoma , in situ , carcinoma in situ , medicine , carcinoma , oncology , breast cancer , cancer , chemistry , organic chemistry
Management of ductal carcinoma in situ has become one of the most controversial topics in breast disease. While mastectomy has been the traditional treatment, many now feel it is excessive in most cases. As a result, a great effort has been made to identify pathobiological characteristics of DCIS that can be used to stratify appropriate treatment decisions. This article reviews efforts to relate pathobiological characteristics to disease management and provides treatment recommendations based on the latest evidence.