Open AccessNew developments in monoclonal antibodies for cancer detection andtherapy
Author(s) -
Goldenberg David M.
Publication year - 1994
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/canjclin.44.1.43
Subject(s) - monoclonal antibody , cancer , cancer therapy , antibody , medicine , targeted therapy , cancer treatment , monoclonal , cancer research , immunology
Monoclonal antibodies have provided clinicians with an intriguing, target-specific approach to cancer management. Used alone or conjugated with drugs, toxins, or radionuclides, monoclonal antibodies have been shown to be useful in the detection and/or treatment of several cancers. Recent advances, such as the development of "humanized" antibodies, promise to increase their effectiveness even more. This article summarizes the status of the in vivo use of monoclonal antibodies for cancer detection and therapy.