Open AccessThe use of neutron beam therapy in the management of locally advanced nonresectable radioresistant tumors
Author(s) -
Hendrickson Frank R.
Publication year - 1988
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/canjclin.38.6.353
Subject(s) - radioresistance , citation , fermilab , principal (computer security) , medicine , neutron , nuclear medicine , radiation therapy , medical physics , library science , physics , nuclear physics , computer science , radiology , operating system
Locally advanced nonresectable radioresistant tumors can often be ablated by external irradiation using high-energy fast neutrons. Long-term remission, with local control rates of 50 to 70 percent, have been reported in a number of very large osteogenic sarcomas, soft tissue sarcomas, melanomas, and adenocarcinomas of the alimentary tract. Malignant salivary gland tumors and prostate carcinomas respond well to neutron therapy, with high remission rates and significantly increased survival, even in locally advanced stages of the disease. Neutron beam therapy is a valuable adjunct in the management of nonresectable cancers that are resistant to conventional therapy.