Open AccessVirilizing hepatoblastoma: Precocious sexual development and partial response of pulmonary metastases to cis‐platinum
Author(s) -
Arshad Raja R.,
Woo Shiao Y.,
Abbassi Val,
Hoy Gregory R.,
Sinks Lucius F.
Publication year - 1982
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/canjclin.32.5.293
Subject(s) - hepatoblastoma , medicine , alpha fetoprotein , oncology , chemotherapy , urology , endocrinology , hepatocellular carcinoma
A 4⅔ year old boy with hepatoblastoma presented with precocious sexual development and an abdominal mass. During the course of disease, serial endocrinologic laboratory invesTIGations were done. along with α‐fetoprotein levels. A significant correlation is noted in these values at diagnosis, postsurgery, and later during a relapse. Ectopic production of chorionic gonadotropins by the tumor is evident. After extensive surgical resection, chemotherapy was started because of metastases. Although the primary tumor failed to respond, the pulmonary metastatic disease showed a greater than 50 percent response rate with cis‐platinum.