Open AccessBlueprint for cancer research: Critical gaps and opportunities
Author(s) -
Elmore Lynne W.,
Greer Susanna F.,
Daniels Elvan C.,
Saxe Charles C.,
Melner Michael H.,
Krawiec Ginger M.,
Cance William G.,
Phelps William C.
Publication year - 2020
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/caac.21652
Subject(s) - blueprint , portfolio , cancer , underpinning , data science , risk analysis (engineering) , computer science , medicine , engineering ethics , management science , business , engineering , mechanical engineering , finance , civil engineering
Abstract We are experiencing a revolution in cancer. Advances in screening, targeted and immune therapies, big data, computational methodologies, and significant new knowledge of cancer biology are transforming the ways in which we prevent, detect, diagnose, treat, and survive cancer. These advances are enabling durable progress in the goal to achieve personalized cancer care. Despite these gains, more work is needed to develop better tools and strategies to limit cancer as a major health concern. One persistent gap is the inconsistent coordination among researchers and caregivers to implement evidence‐based programs that rely on a fuller understanding of the molecular, cellular, and systems biology mechanisms underpinning different types of cancer. Here, the authors integrate conversations with over 90 leading cancer experts to highlight current challenges, encourage a robust and diverse national research portfolio, and capture timely opportunities to advance evidence‐based approaches for all patients with cancer and for all communities.