Open AccessFactors influencing risk‐based care of the childhood cancer survivor in the 21st century
Author(s) -
Dixon Stephanie B.,
Bjornard Kari L.,
Alberts Nicole M.,
Armstrong Gregory T.,
Brinkman Tara M.,
Chemaitilly Wassim,
Ehrhardt Matthew J.,
FernandezPineda Israel,
Force Lisa M.,
Gibson Todd M.,
Green Daniel M.,
Howell Carrie R.,
Kaste Sue C.,
Kirchhoff Anne C.,
Klosky James L.,
Krull Kevin R.,
Lucas John T.,
Mulrooney Daniel A.,
Ness Kirsten K.,
Wilson Carmen L.,
Yasui Yutaka,
Robison Leslie L.,
Hudson Melissa M.
Publication year - 2018
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/caac.21445
Subject(s) - medicine , cancer , population , multidisciplinary approach , intervention (counseling) , intensive care medicine , health care , cancer survivor , childhood cancer , malignancy , gerontology , environmental health , psychiatry , social science , sociology , economics , economic growth
The population of adult survivors of childhood cancer continues to grow as survival rates improve. Although it is well established that these survivors experience various complications and comorbidities related to their malignancy and treatment, this risk is modified by many factors that are not directly linked to their cancer history. Research evaluating the influence of patient‐specific demographic and genetic factors, premorbid and comorbid conditions, health behaviors, and aging has identified additional risk factors that influence cancer treatment‐related toxicity and possible targets for intervention in this population. Furthermore, although current long‐term follow‐up guidelines comprehensively address specific therapy‐related risks and provide screening recommendations, the risk profile of the population continues to evolve with ongoing modification of treatment strategies and the emergence of novel therapeutics. To address the multifactorial modifiers of cancer treatment‐related health risk and evolving treatment approaches, a patient‐centered and risk‐adapted approach to care that often requires a multidisciplinary team approach, including medical and behavioral providers, is necessary for this population. CA Cancer J Clin 2018;68:133‐152 . © 2018 American Cancer Society .