Open AccessPrimary tumor location found to impact prognosis and response to therapy in patients with metastatic colorectal cancer
Author(s) -
Barton Mary Kay
Publication year - 2017
Publication title -
ca: a cancer journal for clinicians
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 62.937
H-Index - 168
eISSN - 1542-4863
pISSN - 0007-9235
DOI - 10.3322/caac.21372
Subject(s) - cetuximab , medicine , colorectal cancer , oncology , primary tumor , chemotherapy , cancer , metastasis
Key Points Patients with mCRC with a left‐sided primary tumor carry a better prognosis than patients with tumors originating on the right side. Adding cetuximab to chemotherapy improves outcomes for patients with left‐sided tumors, but not for those with right‐sided ones. Side of origin should be considered when deciding on therapeutic regimens for patients with mCRC.