Open AccessHow do thiazide and thiazide-like diuretics lower blood pressure?
Author(s) -
Alun D. Hughes
Publication year - 2004
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.3317/jraas.2004.034
Subject(s) - thiazide , medicine , blood pressure , pharmacology
Thiazide diuretics are widely used for the treatment of hypertension, but the mechanism by which these drugs lower blood pressure in the long term remains unknown. This article reviews current knowledge about the hypotensive actions of thiazides and thiazide-like diuretics and discusses possible mechanisms of action.
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