Open AccessReview: Rationale for combination therapy in the treatment of hypertension
Author(s) -
Domenic A. Sica
Publication year - 2002
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.3317/jraas.2002.019
Subject(s) - intensive care medicine , medicine , disease , hypertension treatment , pharmacotherapy , blood pressure
The effective treatment of hypertension still poses many problems. In the last decade it has become apparent that in many patients multi-drug regimens are needed to effect blood pressure control. How best to combine medications and what might be a preferred order of initiating drugs is still open to debate and has proven the substance of many of the published guidelines on this theme. Like most matters in the clinical sector the approach to a disease — in this case hypertension — should remain highly individualised and cognisant of what can be significant cost considerations.