Sinonasal Inverted Papilloma: Epidemiological and Pathological Profile from 15 Cases

Inverted papilloma is a rare benign Sino nasal tumor marked by strong local aggressiveness, a high rate of recurrenceafter surgery and an unpredictable risk of association with squamous cell carcinoma. We retrospectively investigated15 cases of inverted papilloma that were treated between January 2004 and December 2018, diagnosed at thepathological anatomy department, CHU MOHAMMED VI of Marrakech. The objective of this work was to study theepidemiological and anatomopathological profile of these polyps. The sex ratio of 2.75 was clearly predominate inmales with an average age of 40 years. Its main clinical symptoms was manifested by nasal blockage. The radiologicalassessment using CT and nasosinus MRI couple constituted a very important means of the positive diagnosis of theinverted papilloma and of the choice of the operating method. Histological examination showed a papillomata’spolypoid respiratory mucosa, at the level of the chorion, with signs of low grade dysplasia in only one case. Theirhigh potential for local aggressiveness, the fear of a recurrence and the possibility of the occurrence of a malignanttumor require radical management.