Etiological Hypotheses and Facts of Acute Pneumonia

Modern AP concepts are focused exclusively on the infectious nature of the disease and the presence of certain pathogens. Thisbelief determines the principles of treatment, the lack of effectiveness of which remains a concern of health professionals. Thearticle presents a fragment of the study devoted to the etiology of АP. 994 children aged 4 months to 14 years with various formsof so-called community-acquired pneumonia were examined and treated. Bacteriological examination of the material from theinflammation zone was carried out in 542 patients. Experiments on modeling АP and its pleural complications were performedon 44 animals. The obtained results and critical analysis of the literature data and scientific facts allow us to consider bacteriaonly as one of the etiological elements of АP, which is not mandatory in all cases of the disease. Scientifically based revision ofexisting ideas about the causes and mechanisms of AP development leads to the need for a radical change in the principles oftreatment and is a strategic direction in solving the problem.