Open AccessThe Role of Genetics Mutation in Gene Tgm5 in Induce Acral Peeling Skin Syndrome
Publication year - 2019
Publication title -
medical and clinical research
Language(s) - English
Resource type - Journals
ISSN - 2577-8005
DOI - 10.33140/mcr.04.03.03
Subject(s) - chromosome , genetics , long arm , mutation , gene , dermatology , biology , medicine
APS syndrome is a skin-related genetic disorder characterized by painless skin lesions from the upper layer of the skin. Inaddition to the above, sometimes peeling of the skin in the arms and legs also occurs. Skin peeling usually appears at birth, butcan begin in childhood or later in life. APS syndrome is caused by the mutation of the TGM5 gene, which is based on the longarm of chromosome 15 as 15q15.2.