Phytochemical and Pharmacological Study on the Leaves of Bauhinia Purpurea L. for Antilithiatic Activity

The main purpose of this study was to investigate the impact of ethanolic concentrate of Bauhinia purpurea L. leaves on lithiaticaction in rat. Twenty four rats were divided into 6 groups comprising four animals per groups. The blood was collected fromthe retro-orbital sinus; serum was separated by centrifugation and analyzed for creatinine and uric acid. Both kidneys fromeach animal were removed and sectioned for histopathological examination. The results were expressed as mean ± standarderror mean (SEM) and the statistical significance was assessed using one-way analysis of variance (ANOVA) followed byDunnett’s comparison test and p<0.05 was considered significant. In the present in-vivo study, renal stone inciting treatmentto rodents came about in hyper-oxaluria. Ethanolic concentrate of B. purpurea L. was exposed to antilithiatic action in rodentswhere ethylene glycol 0.75% (v/v) utilized as the causing lithiasis specialist. Ethanolic concentrate of B. purpurea (at 100and 200 mg/kg) showed a portion subordinate noteworthy enemy of lithiatic action on treatment. The concentrate portion of100 mg/kg likewise caused decrease of Ca, oxalates, P and creatinine in blood serum level the outcomes were found factuallynoteworthy. The impact of ethanol concentrate of this movement was discovered critical than the reference standard. By andlarge investigation uncovers that the ethanolic concentrate of B. purpurea L. demonstrates the mellow to direct antilithiaticmovement with correlation with cystone.