Exophthalmos and Blindness Revealing a Non-Hodgkin’s Malignant Lymphoma Type B with High Grade of Malignancy

Background: Non-Hodgkin’s lymphomas represent a heterogeneous group of haematological disorders characterizedby a malignant monoclonal proliferation of the lymphoid system (B or T cells). Orbicatory lolisation is rare, it is seenmainly in adults.Case Report: We report the case of a 79-year-old patient with a high-grade NHML, revealed by blindness and leftexophthalmos evolving for 3 months. Ophthalmological examination revealed left blindness with axil exophthalmosgrade 1. MRI cranio-orbital objectified a left orbital processe lesion intra and extra conical associated with a mucosalthickening of the cavum with left necrotic jugulocarotidian adenopathies. A biopsy of the cavum and ADP objectifieda NHML of type B with high grade of malignancy.Result: The patient was put on induction chemotherapy first before being placed on radiotherapy. The evolution wasmarked by the regression of the left exophthalmia.Conclusion: The NHML is characterized by an extreme clinical polymorphism, especially in the cervicofaciallocalizations, make the diagnosis difficult and lead to a delay in management.