Early Specific Metabolic Markers of Deadaptation of the Organism of Pregnant Women in Preeclampsia in The Conditions of the Hard North

Preeclampsia is one of the most common obstetric pathologies affecting the level of maternal and perinatal loss. Preeclampsia is manifested maladjustment state organ of the body for pregnancy, depending on the climatic conditions due to changes in temperature and atmospheric pressure. Objective: To identify the frequency of severe preeclampsia in the Far North and the determination of the most sensitive markers of the state of maladjustment pregnant. Results: the incidence of preeclampsia in the northern areas of the Irkutsk region is higher than in its southern region. The frequency of severe preeclampsia in these regions did not differ. The most sensitive markers of the state of maladjustment pregnant as a mild form of preeclampsia are the concentration ratios dienes and cortisol.