Cognitive Impairment Associated with Chronic Alcohol Dependence: Recent Advances in The Understanding of Disease Pathogenesis

At present, a large increase in global alcoholics, the resulting problems associated with alcohol dependence cognitive dysfunction has becomeincreasingly serious, the domestic and foreign research shows that long-term excessive drinking seriously damage the body organs, thispaper mainly study the influence of the alcohol dependence on the central nervous system, from signal transduction, oxidative stress andneuritic response, neurotransmitter release and its receptor, nutrition metabolism, brain structure change analysis of alcohol dependencesummarized research progress to do related to the pathogenesis of cognitive impairment.