The Sea Star Igkappa Gene and The Ophuirid Igkappa Gene Vaccinations to HRP (Horse-radish Peroxydase)

The main point of the sea star immunology, of the ophuirid immunology remain the discovery of the INVERTEBRATE PRIMITIVEANTIBODY (IPA), the IGKAPPA GENES, with Ig sites which imply the COMPLEMENT SYSTEM, to be initiated: 9 componentgenes from C1 to C9 have been updated these last years, in sea star genome, in ophuirid one. These primitive antibodies wereobtained after immunizations to the enzyme HRP (Horse-radish peroxydase). It is the first time we observe vaccinations ininvertebrates. We have discovered, for the first time also, in these same Invertebrate a FC receptor gene, a Fab gene whichcorroborate the presence of IPA. The transcriptomes are given. It is the first time, we can speak of Adaptative Immunity, inEchinoderms, in Invertebrates Since many years, even since a century long, the notion of Antibody was out of the speech ofimmunologists. To speak of that made you as an outlaw. It is time to look with genomic studies which confirm which assert nowevidence that 3 classes of Echinoderms out of 5 possess an Igkappa gene, a FC receptor gene. I recall these classent: the Asteridswith Asterias rubens, the Ophuirids with Ophiocomina nigra and the Crinoïds.