Open AccessFatigue in Multiple Sclerosis: Current Concepts and Future Challenges
Publication year - 2016
Publication title -
journal of clinical and experimental immunology
Language(s) - English
Resource type - Journals
ISSN - 2475-6296
DOI - 10.33140/jcei.01.01.05
Subject(s) - multiple sclerosis , affect (linguistics) , cognition , disease , motor symptoms , physical medicine and rehabilitation , sensory system , medicine , psychology , neuroscience , physical therapy , psychiatry , parkinson's disease , communication
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). During the disease process, affected patients can experience sensory, motor, cognitive and emotional symptoms. Fatigue is also a common and debilitating complain that can affect up to 75% of MS patients at some point during their life [1]. By definition, it is a reversible subjective lack of mental and/or physical energy that can alter normal functioning. The symptom severity can fluctuate in a way that it is usually higher at the end of the day, and during hot or humid environment [1].