Open AccessChondrosarcoma-A Multi-Faceted Entity
Publication year - 2020
Language(s) - English
DOI - 10.33140/ijor.03.01.09
Subject(s) - chondrosarcoma , medicine , primary bone , enchondroma , scapula , skull , anatomy , osteochondroma , craniofacial , metaphysis , pelvis , brachyury , pathology , biology , mesoderm , psychiatry , biochemistry , embryonic stem cell , gene
Chondrosarcoma (CS) accounts for 20-27% of all primary malignanttumors of bone mostly seen in older age group [1]. It may beprimary or secondary occurring in 2nd to 5th decade. The longbones especially the metaphysis are the most common sites. Axialskeleton, skull, jaw, small bones of hand and feet are other sitesthat can be involved. Though rare, extraskeletal CS may occuranywhere in the body. The conventional CS are primary or secondary.Primary chondrosarcoma may be intramedullary or Juxtacortical.Secondary CS arises from Osteochondroma or Enchondroma. Nonconventional CS are clear cell, myxoid, mesenchymal, extraskeletal,and dedifferentiated. Usual distribution of these tumors is long bones(45%) or pelvis (25%). The spine (7%), scapula (5%), cervicalspine (6-7%), craniofacial bones (2%), hand and foot are rarelyaffected [2].