Open AccessAt A Glance On Kothala himbutu
Publication year - 2019
Publication title -
international journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
ISSN - 2475-5451
DOI - 10.33140/ijdmd.04.03.5
Subject(s) - lipolysis , hormone sensitive lipase , sri lanka , lipase , stickleback , adiponectin , traditional medicine , diabetes mellitus , in vitro , insulin resistance , mode of action , obesity , biology , adipose tissue , endocrinology , pharmacology , medicine , biochemistry , fish <actinopterygii> , geography , enzyme , environmental planning , fishery , tanzania
Kothala himbutu (Salacia reticulate; SR) is a very useful medicinalplant in Sri Lanka and the southern region of India. SR containssalacinol and kotalanol neosalacinol and neokotalanol which canisolated from the Salacia species by using iron pair chromatography[1& 2]. It is a woody climber and widely used in Ayurvedic medicinefor diabetes and obesity treatment. Previously, the action of SR fordiabetes is not described properly. Researchers tried to explore theeffect of SR and found that it has an alpha glucosidase inhibitoractivity in invitro study. Moreover, SR may increase lipolysisand reduce insulin resistance by enhancing mRNA expression forhormone sensitive lipase (HSL) and adiponectin [3].