Metastasis to the scalp as the first finding of Clear Cell Carcinoma of the Kidney: Case Report and Review of the Literature
Publication year - 2020
Publication title -
international journal of cancer research and therapy
Language(s) - English
Resource type - Journals
ISSN - 2476-2377
DOI - 10.33140/ijcrt.05.01.04
Subject(s) - medicine , scalp , nephrectomy , renal cell carcinoma , histopathology , malignancy , pathology , metastasis , lesion , clear cell renal cell carcinoma , clear cell , neoplasm , occult , asymptomatic , cancer , kidney , dermatology , alternative medicine
The case of a 70-year-old man, with no previous pathological history, who consulted for post-traumatic injury to the scalp; it was managed as a benign lesion and it was taken to surgical resection with a histopathology and immunohistochemistry study compatible with clear cell neoplasia of metastatic renal origin. Extension studies were performed with findings of pulmonary nodules that suggested metastatic disease and with a finding of right renal mass. Radical nephrectomy is performed confirming the diagnosis of renal cell carcinoma subtype clear cells. A review of the literature was carried out, which shows that a skin lesion may be the first symptom of an internal neoplasm, with breast cancer being the most frequent one reported in the literature in cutaneous metastases. The finding of a posttraumatic injury to the scalp as the first sign of a clear cell carcinoma of renal origin is very rare. The diagnosis of skin metastases requires a histopathology and immunohistochemistry study, which must be timely because it may be the first link in the research chain to detect an occult neoplasm. In conclusion, the surgeon who faces a soft tissue tumor on the scalp must consider the characteristics of the lesion, the patient’s risk factors in an articulated way that allows him to suspect malignancy in a skin lesion and that allows him diagnose a previously unknown and asymptomatic neoplasm.
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