An Unsual Site about Small Cells Osteosarcoma Parietal Region and Classique Osteosarcoma Occipital Region Mimicking Meningioma with Literature Review Management and Outcome

Primary osteosarcoma (OS) is the second most common primary bone malignancy, the first being multiplemyeloma. OS occurs in the second decade, with a predilection for ends of long bones. Head and neck involvement isseen in 2-9% with extragnathic craniofacial bones in 1–2% of cases. Small Cell OS (SCO) constitutes 1.3-4% of allOS, skeletal distribution and age range being similar.Materials and Methods: We report two rare osteosarcoma and we done the review of the literature about themanagement and the outcome about intracranial osteosarcoma in our department of neurosurgery.Results: It is two osteosarcoma cases about a 72-year-old man and one 49-year-old man who both mimiking firstmeningioma. The first case is an unusual site parietal and the second case is occipital. The both benefited surgerywith excision and exam of histology confirm diagnosis. But the first case died 15 days after surgery in intensive unitcare and the second cases died after one year, he benefited surgery and chemotherapy.Conclusion: Small cell osteosarcoma (SCO) is an extremely uncommon entity that mainly involves the metaphysicsof long bones and, rarely, the skull. Histopathology is the key to establishing the correct diagnosis, including subtyping for appropriate management and prognostication, as radiological features are not specific.