Open AccessThe Revelations of Acute Kidney Injury in Cases of Acute Febrile Illness – A Hospital Based Observational Study from North Eastern India
Author(s) -
Kallol Bhattacharjee,
Roy Sanjeeb,
PD Balamurali,
Nabaruna Paul
Publication year - 2020
Publication title -
advancements in journal of urology and nephrology
Language(s) - English
Resource type - Journals
ISSN - 2689-8616
DOI - 10.33140/ajun.02.01.04
Subject(s) - medicine , acute kidney injury , etiology , leptospirosis , dengue fever , incidence (geometry) , scrub typhus , malaria , creatinine , observational study , intensive care medicine , immunology , pathology , physics , optics
Background: Clinicians across the globe refer to the published KDIGO definition of Acute Kidney Injury (AKI) asone of the following:• An increase in serum creatinine by ≥0.3 mg/dl (≥26.5 µmol/l) within 48 hrs• An increase in serum creatinine to ≥1.5 times baseline within the previous 7 days• Urine volume <0.5 ml/kg/h for 6 hrsAcute febrile illnesses are a common cause of AKI in hospitalized patients. The present study was undertaken toevaluate the incidence of AKI in patients presenting with acute febrile illness and also study the different etiologicalfactors responsible for acute febrile illness.Materials and Methods: The study included 200 patients of acute febrile illness admitted in Silchar Medical CollegeAnd Hospital in the Department of Medicine over a period of 24 months. The data regarding the various causes suchas the etiology of fever, kidney function tests and other parameters of the cases were obtained and analyzed usingsimple statistical methods.Results and Observations: A total of 52 patients (26%) with acute febrile illness due to etiologies like Leptospirosis,Falciparum Malaria, Enteric fever, Dengue, Scrub Typhus, and mixed Malaria, etc developed AKI out of the 200admitted cases presenting with acute febrile illness.Conclusion: The incidence of AKI is common in hospitalized patients of acute febrile illness and a thorough evaluationand detailed clinicobiochemical monitoring of the patients are necessary as it has varied etiology and often lead toan unfavorable or even unexpected outcome.