Open AccessAntibacterial Activity of Aqueous Extracts of Malus Domestica Against Some Bacterial Pathogens
Publication year - 2019
Publication title -
archives of infectious diseases and therapy
Language(s) - English
Resource type - Journals
ISSN - 2577-8455
DOI - 10.33140/aidt.03.02.4
Subject(s) - staphylococcus aureus , antibacterial activity , pomace , escherichia coli , chemistry , food science , extraction (chemistry) , enterococcus faecalis , pseudomonas aeruginosa , microbiology and biotechnology , pseudomonas , antibiotics , bacteria , chromatography , biology , biochemistry , genetics , gene
The present study was designed to evaluate the antibacterial activity of aqueous extracts of Malus domestica (peel andpomace) against food-borne pathogens (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcusfeacalis). Extraction conditions (temperature and time) were optimized to obtain maximum yield by using response surfacemethodology. Antibacterial potentials of the extracts were examined through disc inhibition zone technique and the resultswere compared with commercial antibiotic. Results Indicated that maximum antibacterial activity was shown by peel extractagainst Staphylococcus aureus with average zone of inhibition 19.25±0.89 mm while pomace 12.75±0.71 mm. Maximumrecovery for water soluble compounds from peel was obtained at 70ºC followed by 90ºC and 50ºC, which was 16.33, 14.67and 12.67%, respectively. The extraction yield was also increased but after 30 minutes. The antibacterial activities of peelextract were comparable with commercial antibiotic (20.13±0.83 mm). Escherichia coli were appeared to be the most resistantwith inhibition induced by the extracts of peel 15.00±1.07 mm and pomace11.50±0.53mm.