Open AccessRole of RAGE, sRAGE & esRAGE In Inflammation & Diseases
Publication year - 2020
Publication title -
advances in bioengineering and biomedical science research
Language(s) - English
Resource type - Journals
ISSN - 2640-4133
DOI - 10.33140/abbsr.03.01.02
Subject(s) - immunoglobulin superfamily , rage (emotion) , glycation , inflammation , receptor , immunoglobulin domain , antibody , immunology , medicine , extracellular , immunoglobulin g , cancer research , biology , microbiology and biotechnology , neuroscience
Receptor for advanced glycation end product (RAGE) is a mutliligand pro-inflammatory pattern recognition receptor (PRR) and plays a role in in many pathologic conditions like diabetes, cancer, cardiovascular and neurodegenerative diseases. It belongs to the immunoglobulin superfamily of cell surface molecules and contains one V-type and two C-type immunoglobulin (Ig) domains in extracellular region [1-3].