Open AccessMethenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT
Author(s) -
Chris Harding,
Thomas Chadwick,
Tara Homer,
Jan Lecouturier,
Helen Mossop,
Sonya Carnell,
Alaa Abouhajar,
Luke Vale,
Gillian Watson,
Rebecca Forbes,
Stephanie Currer,
Robert Pickard,
Nikesh Thiruchelvam,
Karen Guerrero,
Katherine Walton,
Henry Lazarowicz,
Ased Ali
Publication year - 2022
Publication title -
hta on dvd/health technology assessment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.426
H-Index - 126
eISSN - 2046-4924
pISSN - 1366-5278
DOI - 10.3310/qoiz6538
Subject(s) - medicine , urinary system , nitrofurantoin , bacteriuria , randomized controlled trial , antibiotics , antibiotic prophylaxis , antibiotic resistance , surgery , microbiology and biotechnology , biology
Daily, low-dose antibiotic prophylaxis is the current standard care for women with recurrent urinary tract infection. Emerging antimicrobial resistance is a global health concern, prompting research interest in non-antibiotic agents such as methenamine hippurate, but comparative data on their efficacy and safety are lacking.