Isolasi Dan Identifikasi Senyawa Kimia Monoterpen Dari Fraksi Etilasetat Daun Keji Beling (Strobilanthes crispa (L.) Blume) Yang Mempunyai Daya Sitotoksik | Zendy

Lilik Sulastri | Zendy; Ristanti Mega Lestari | Zendy; Partomuan Simanjuntak | Zendy

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Isolasi Dan Identifikasi Senyawa Kimia Monoterpen Dari Fraksi Etilasetat Daun Keji Beling (Strobilanthes crispa (L.) Blume) Yang Mempunyai Daya Sitotoksik

Author(s) -

Lilik Sulastri,

Ristanti Mega Lestari,

Partomuan Simanjuntak

Publication year - 2021

Publication title -

jurnal fitofarmaka indonesia

Language(s) - English

Resource type - Journals

eISSN - 2541-2329

pISSN - 2356-0398

DOI - 10.33096/jffi.v8i1.721

Subject(s) - maceration (sewage) , chemistry , chromatography , ethyl acetate , brine shrimp , fractionation , traditional medicine , column chromatography , hexane , thin layer chromatography , medicine , materials science , composite material

Isolation and identification one of chemical compound mono-terpene from Keji beling plant (local name) (Strobilanthes crispa) has been done. Extraction was carried out by maceration of the keji beling leaf powder with ethanol 96%, then partitioned with water-ethyl acetate. Ethylacetate extract was isolated and purified by a cytotoxic guide fractionation system with Brine Shrimp Lethality Test (BSLT) on column chromatography (SiO2; n-hexane - ethylacetate = 20 : 1); and preparative Thin Layer Chromatography (TLC) (SiO2; n-hexane - ethylaseate = 10 : 1) which gave one compound in oily form. Based on identification by infra red spectra and gas chromatography-mass spectra (GC-MS), the compound is a monoterpene D-limone which has a cytotoxic power of 73,11 ppm.

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