Open AccessPENGGUNAAN PENANDA BIOLOGIS ANGIOGENIK RASIO s-Flt1 DAN PIGF SEBAGAI PREDIKTOR PREEKLAMSIA
Author(s) -
Yelvi Levani
Publication year - 2019
Publication title -
medical and health science journal
Language(s) - English
Resource type - Journals
eISSN - 2549-7596
pISSN - 2549-7588
DOI - 10.33086/mhsj.v3i1.920
Subject(s) - preeclampsia , medicine , angiogenesis , proteinuria , placental growth factor , pregnancy , vegf receptors , vascular endothelial growth factor , biology , genetics , kidney
Preeclampsia is a leading cause of maternal death worldwide. Preeclampsia involves multi-organ and characterized by hypertension and proteinuria. One of the hypothesis pathogenesisin preeclampsia is placental insufficiency. Its causing imbalance between angiogenic and antiangiogenic factors in maternal circulation. This imbalance factors are responsible for systemic vasoconstriction. However, until now, there is no predictor for preeclampsiain high risk pregnancy. Therefore, this review briefly describes the recent studies about utility of biologic angiogenesis marker, such as s-Flt1 and PIGF as predictor in preeclampsia