Open AccessEstimation of Selenium Level in Serum of Iraqi Thalassemic Patients After Ferritin Assay
Author(s) -
Sundus Kh. Al-Khazraji
Publication year - 2010
Publication title -
almustansiriya journal of pharmaceutical sciences/al-mustansiriyah journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2959-183X
pISSN - 1815-0993
DOI - 10.32947/ajps.v7i1.319
Subject(s) - selenium , medicine , ferritin , serum ferritin , thalassemia , trace element , physiology , antioxidant , gastroenterology , blood transfusion , surgery , chemistry , biochemistry , organic chemistry
Background: Selenium, a trace element with antioxidant properties, decreased in patients with blood disorders.Objective: To see if blood transfusion in those patients with thalassemia corrects the level of selenium in their blood.Materials & Methods: Seventeen patients enrolled in this small study, ten of them females and seven were males, their ages were ranged from 1.5-73 years.Ferritin and selenium levels were estimated using Mini-Vidas and atomic absorption technique respectively.Results: Decreased selenium level in both non-bloods transfused (0.33±0.17ppm) and blood transfused patients (0.30±0.24ppm) show no effect of blood transfusion on the level of this trace element.
Conclusion: Selenium supplement is the only way to elevate the level of this element in the body with some precautions of selenium toxicity. Further studieson this subject are recommended.