Open AccessProtection of Chicken against Bacterial Infection by Immunization with Bacterial Subcellular Fractions
Author(s) -
Khalid K. AL.Bayatti,
Samia K. Mahmood,
Ali A. Abdul-Abbas
Publication year - 2007
Publication title -
almustansiriya journal of pharmaceutical sciences/al-mustansiriyah journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2959-183X
pISSN - 1815-0993
DOI - 10.32947/ajps.v4i1.382
Subject(s) - cytoplasm , immunization , antigen , subcellular localization , escherichia coli , microbiology and biotechnology , somatic cell , biology , immunity , bacterial outer membrane , cell wall , immunology , immune system , gene , biochemistry
The current studies were undertaken to assess the ability of various subcellular fraction of E.coli to induce protection against challenge with E.coli in chicken.Immunization with as little as 12.5 μg of cytoplasmic membrane conferred 65% protection. In addition cell wall and somatic antigen conferred 55% and 25%protection respectively. These results indicate the usefulness of cytoplasmic membrane and cell wall in the induction of active immunity against pathogenic E.coli in chicken.