Open AccessThe Effect of Smoking on the Some Trace Elements and Cortisol Hormone Concentration in Serum
Author(s) -
Ali Saad Elewi
Publication year - 2012
Publication title -
almustansiriya journal of pharmaceutical sciences/al-mustansiriyah journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2959-183X
pISSN - 1815-0993
DOI - 10.32947/ajps.v11i1.236
Subject(s) - nicotine , selenium , hormone , serum concentration , medicine , endocrinology , chemistry , zoology , biology , organic chemistry
The effect of different doses of smoking on the some trace elements (Se, Zn, Pb, Cu) and cortisol hormone concentration have been studied.Four groups of smokers were used in this study to investigate the effect of smoking in trace element and cortisol hormone concentration in smokers andcompare the finding with nonsmokers group (control group). Mean values of cortisol hormone concentration in group I (consumed 10- 20 cigar per day with 0.4mg nicotine/cigar) were found to be significantly higher (p 0.01) in comparison with the value of control group and high significantly higher (p 0.001) in group II who consumed 10-20 cigar per day with 0.8 mg nicotine/cigar, and high significantly higher (p 0.001) in group III, IV (consumed 40 or more cigar per day with 0.4 and 0.8 mg nicotine/cigar, respectively).Serum selenium concentrations in smokers were below control group among all smoker groups, and the concentrations of selenium were depression increasing with increasing doses of smoking and nicotine in cigar.Significantly increase in concentration of Cu (p 0.001) in group III, IV in comparison with control group while non significant increase (p 0.05) in group I, II.No effect of smoking in the concentration of Zn in serum of all smoker groups.Pb serum concentration in smoker were found to be higher than control group, and the increasing in pb concentration proportion with increasing dosesof smoking and nicotine in cigar.