Open AccessAssay of Ampicillin in capsule Dosage Form Manufactured by Different Pharmaceutical Manufacturing Factories available in Iraq.
Publication year - 2019
Publication title -
almustansiriya journal of pharmaceutical sciences/al-mustansiriyah journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2959-183X
pISSN - 1815-0993
DOI - 10.32947/ajps.19.03.0406
Subject(s) - ampicillin , dosage form , chromatography , stock solution , chemistry , capsule , calibration curve , antibiotics , biology , biochemistry , botany , detection limit
The assay of Ampicillin is carried out by HPLC (High performance liquid chromatography) system to calculate the weight of the active constituent of the drug in this dosage form. In this work we study six samples of Ampicillin 250 mg capsule manufactured by different pharm-aceutical companies available in Iraq to evaluate the content of drug in this dosage form. This has been achieved by making calibration curve of different concentrations of stock solution, using standard ampicillin tri hydrate (Reference Standard Ampicillin) USP, we obtained different reading of the area under the peak (AUP) which followed straight – line equation.