Open AccessMilk and cow’s meat allergy in a child: A clinical case
Author(s) -
Maria Luís Marques,
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Inês Falcão,
Moisés LabradorHorrillo,
Helena Falcão,
Liliana Cunha,
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AUTHOR_ID,
AUTHOR_ID,
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Publication year - 2021
Publication title -
revista portuguesa de imunoalergologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.13
H-Index - 5
eISSN - 2184-3856
pISSN - 0871-9721
DOI - 10.32932/rpia.2021.12.072
Subject(s) - milk allergy , irritability , medicine , allergy , food allergy , oral food challenge , bovine serum albumin , immunoglobulin e , red meat , anaphylaxis , food science , immunology , biology , antibody , pathology , menopause
Allergy to bovine serum albumin is the main predictor of beef allergy associated with cow’s milk proteins allergy. We report a case of a 3-year-old child with cow’s milk proteins allergy since the age of 6 months who, after some ingestions of beef, developed episodes of irritability, urticaria and syncope. Specific IgE to beef, oral food challenge with medium rare cooked beef and specific IgE to bovine serum albumin were all positive, but an oral food challenge with well cooked beef was tolerated. Allergy to bovine serum albumin is not usually associated with severe reactions, since it is a thermolabile protein, however, the process of cooking meat may be insufficient to have an effect on the complex matrix of meat and associated serum albumins. The irregular pattern of the episodes and the previous diagnosis of cow’s milk proteins allergy may act as confounding factors leading to a delayed diagnosis.