Open AccessAcute kidney injury associated with COVID-19 infection: a case report
Author(s) -
Tiago Isidoro Duarte,
Fernando Caeiro,
Mário Góis,
Antonio Parejo Matos,
Helena Viana,
César Vieira,
Jorge Paulos,
Paulo Paixão,
Bruno Augusto de Faria Matos,
Nuno Germano,
Fernando Nolasco,
Lisboa Egas Moniz – Cooperativa de Ensino Superior Crl
Publication year - 2021
Publication title -
revista portuguesa de nefrologia e hipertensão
Language(s) - English
Resource type - Journals
eISSN - 2183-1289
pISSN - 0872-0169
DOI - 10.32932/pjnh.2021.10.146
Subject(s) - medicine , vacuolization , acute kidney injury , kidney , pathology , acute tubular necrosis , tubule , covid-19 , kidney disease , lesion , nephrology , disease , infectious disease (medical specialty)
SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.