Open AccessModification of Heterocycles by Amidoalkylation
Author(s) -
Olga N. Gorunova
Publication year - 2021
Publication title -
inèos open
Language(s) - English
Resource type - Journals
ISSN - 2658-5618
DOI - 10.32931/io2113r
Subject(s) - enantioselective synthesis , intermolecular force , chemistry , organic chemistry , biochemical engineering , catalysis , combinatorial chemistry , engineering , molecule
The functionalized derivatives of heterocyclic compounds find extensive application in medicine, agriculture, and many fields of chemistry as precursors for more complex products that display remarkable biological and catalytic activities. A whole range of different heterocycles can be obtained by intra- or intermolecular amidoalkylation. This review presents the examples of successful application of the reactions of C-amidoalkylation, in particular, enantioselective reactions for the modification of heterocycles and outlines the prospects of their further application.