Open AccessMechanochemical Technology for the Regulation of the Solubility of Anthelmintic Drugs Using Polymers
Author(s) -
С. С. Халиков
Publication year - 2021
Publication title -
inèos open
Language(s) - English
Resource type - Journals
ISSN - 2658-5618
DOI - 10.32931/io2108r
Subject(s) - solubility , anthelmintic , bioavailability , polymer , drug , chemistry , organic chemistry , pharmacology , medicine , veterinary medicine
Controlling the solubility of poorly water-soluble drugs remains one of the major challenges in the development of new effective drugs. The use of polymers is one of the promising routes for increasing the solubility of drug substances. This review summarizes the results of investigations on the application of oligosaccharides, polysaccharides, and other polymers to increase the solubility and bioavailability of anthelmintic drugs, which relate to different classes of organic compounds, by mechanochemical methods.