Open AccessPresumed Ocular Tuberculosis – Challenges in Diagnosis
Author(s) -
Sarah Sathyapriya,
AUTHOR_ID,
Loh Chow Chin,
Wan Hazabbah Wan Hitam,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2022
Publication title -
international conference on public health and well-being
Language(s) - English
Resource type - Conference proceedings
ISSN - 2659-2096
DOI - 10.32789/publichealth.2021.1010
Subject(s) - medicine , tuberculosis , mantoux test , ocular tuberculosis , quantiferon , mycobacterium tuberculosis , dermatology , serology , surgery , tuberculin , pathology , immunology , latent tuberculosis , antibody
Mycobacterium tuberculosis has a large spectrum of extra-pulmonary manifestations,and ocular tuberculosis is one of them. Diagnosis of ocular tuberculosis is oftenpresumptive due to its extreme variability of ocular manifestations and difficultyisolating the organism through biopsy or culture. We report three cases of primaryocular tuberculosis with varied clinical presentations, namely neuroretintis,panuveitis, and occlusive vasculitis. Patients were aged 23 to 45 presented withsymptoms of blurring of vision from 3 days to one week prior to presentation. Visualacuity ranged from 6/18 to 2/60. For all three cases, chest X-ray and serologicalinvestigation for infective causes were normal. Mantoux test and TB Quantiferon testwere negative, and ESR was raised for the first two cases. Mantoux was positive, and ESRwas not raised for the third case. Patients were diagnosed to have Presumed OcularTuberculosis. An anti-tubercular therapy was administered. There was significantimprovement at post-initiation of medication. A high index of clinical suspicion iscrucial due to the diverse clinical presentations of ocular tuberculosis. Earlyinitiation of anti-tubercular therapy is vital for successful treatment.