Open AccessPromising Male Hormonal Contraceptive are Well Established Soon a Reality
Author(s) -
Eka Rusdianto Gunardi,
Arnold Soetarso,
Putri Addina
Publication year - 2016
Publication title -
indonesian journal of obstetrics and gynecology
Language(s) - English
Resource type - Journals
eISSN - 2338-7335
pISSN - 2338-6401
DOI - 10.32771/inajog.v3i4.60
Subject(s) - progestin , medicine , hormonal contraception , testosterone (patch) , hormone , male contraceptive , gynecology , physiology , androgen , population , endocrinology , family planning , research methodology , environmental health
Objective: To understand the modalities used for male hormonal
contraception.
Methods: Literature review
Conclusion: Male contraceptive methods are still limited but hormonal
contraceptive methods are being developed. The basic
mechanism of male hormonal contraception is to inhibit spermatogenesis
by suppression of the hypothalamic-pituitary-testicular axis
function. Administration of testosterone or androgen derivative that
is given in combination with progestin or GnRH antagonist shows
that male hormonal contraceptive is reversible, effective, and acceptable
as a male contraceptive method. However, no method of male
hormonal contraceptive is ready for clinical use and marketed due
to limited studies.
[Indones J Obstet Gynecol 2015; 3-4: 239-243]
Keywords: GnRH antagonist, male hormonal contraceptive, progestin,
testosterone