Promising Male Hormonal Contraceptive are Well Established Soon a Reality | Zendy

Eka Rusdianto Gunardi | Zendy; Arnold Soetarso | Zendy; Putri Addina | Zendy

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Promising Male Hormonal Contraceptive are Well Established Soon a Reality

Author(s) -

Eka Rusdianto Gunardi,

Arnold Soetarso,

Putri Addina

Publication year - 2016

Publication title -

indonesian journal of obstetrics and gynecology

Language(s) - English

Resource type - Journals

eISSN - 2338-7335

pISSN - 2338-6401

DOI - 10.32771/inajog.v3i4.60

Subject(s) - progestin , medicine , hormonal contraception , testosterone (patch) , hormone , male contraceptive , gynecology , physiology , androgen , population , endocrinology , family planning , research methodology , environmental health

Objective: To understand the modalities used for male hormonal contraception. Methods: Literature review Conclusion: Male contraceptive methods are still limited but hormonal contraceptive methods are being developed. The basic mechanism of male hormonal contraception is to inhibit spermatogenesis by suppression of the hypothalamic-pituitary-testicular axis function. Administration of testosterone or androgen derivative that is given in combination with progestin or GnRH antagonist shows that male hormonal contraceptive is reversible, effective, and acceptable as a male contraceptive method. However, no method of male hormonal contraceptive is ready for clinical use and marketed due to limited studies. [Indones J Obstet Gynecol 2015; 3-4: 239-243] Keywords: GnRH antagonist, male hormonal contraceptive, progestin, testosterone

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