Open AccessRecurrence-Free Survival Stage IB1-IIA2 Intermediate Risk Group (Based on Kartu Delgado) Cervical Carcinoma after Radical Surgery and Adjuvant Radiotherapy
Author(s) -
Andi Friadi
Publication year - 2016
Publication title -
indonesian journal of obstetrics and gynecology
Language(s) - English
Resource type - Journals
eISSN - 2338-7335
pISSN - 2338-6401
DOI - 10.32771/inajog.v2i3.397
Subject(s) - medicine , radical hysterectomy , adjuvant radiotherapy , cervical cancer , radical surgery , stage (stratigraphy) , cervical carcinoma , surgery , adjuvant , adjuvant therapy , radiation therapy , cancer , chemotherapy , paleontology , biology
Objective: To evaluate the benefits of adjuvant radiotherapy (ART)
based on Kartu Delgado (simple form of Gynecologic Oncology
Group (GOG) scoring system) aimed at women with early stage cervical
cancer after radical surgery.
Method: Fifty patients were enrolled for this study. Twenty one patients
from 2011-2012 were given ART following surgery based on
their Kartu Delgado score from as follows: score 120 were given ART. Their score and
recurrence were compared with 29 patients who were treated in
2009-2010 (based on single prognostic factor).
Result: We observed eighteen recurrences for the duration this
study. Thirteen patients from the period of 2009-2010 and five patients from the period of 2011-2012. Most recurrences occurred in
patients from 2009-2010 with score > 120 but were not designated
ART. Two-years recurrence-free survival (RFS) for subjects with
score 120 with ART was 64.29%.
Conclusion: Adjuvant radiotherapy given based on Kartu Delgado
reduced the number of recurrences in women with stage IB-IIA cervical cancer after treated by surgery.
[Indones J Obstet Gynecol 2014; 3: 146-152]
Keywords: cervical carcinoma, intermediate risk, prognostic factor,
radical hysterectomy