Open AccessN-ALKOXYMETHYL DERIVATIVES OF 2-AMINOTHIAZOLE AND THEIR PROTECTIVE PROPERTIES
Author(s) -
Vagif Farzaliyev,
М. Т. Аббасова,
B.G. Babaeva,
М. А. Мирзоева,
G.M. Kulieva,
L. R. Safarova,
N. A. Alieva
Publication year - 2020
Publication title -
kimya problemləri
Language(s) - English
Resource type - Journals
eISSN - 2522-1655
pISSN - 2221-8688
DOI - 10.32737/2221-8688-2020-4-427-435
Subject(s) - formaldehyde , diesel fuel , amine gas treating , chemistry , nuclear chemistry , organic chemistry , petroleum product , petroleum
Conditions for alkoxymethylation of 2-aminothiazole with semiformals obtained by the interaction of aliphatic alcohols with formaldehyde were worked out. Alkoxymethylation was performed by means of preliminary preparation of the semiformal of appropriate hydroxylcontaining compounds followed by interaction of semiformal with equimolar amount of 2- aminothiazole. The structure of the obtained compounds was acknowledged by means of IR and NMR 1 H spectroscopy. It was established that the reaction of the alkoxymethylation proceeds in the amino form of the starting 2-aminothiazole to form an appropriate monosubstituted Nalkoxymethyl derivative. As a result of microbiological tests, it was established that these compounds have high bactericidal properties against microorganisms which affect petroleum products and, at a concentration of 0.5%, completely protect both M-8 lubricating oil and diesel fuel from damage by bacteria even in terms of their forced infection. It found that at a concentration of 100 mg/l the obtained compounds protect the CT-3 steel from acid corrosion, moreover N-(isopropoxymethyl)thiazol-2-amine has the greatest protection effect.