Open AccessUSING OPTICALLY ACTIVE CHIRAL CROWN ETHER AT ENANTIOMERIC SEPARATION OF AMINES
Author(s) -
Ulviyya Hasanova,
Z.O. Qahramanova,
Parvana Huseynova
Publication year - 2021
Publication title -
azərbaycan kimya jurnalı/azerbajčan himiâ žurnaly
Language(s) - English
Resource type - Journals
eISSN - 2522-1841
pISSN - 0005-2531
DOI - 10.32737/0005-2531-2021-3-59-62
Subject(s) - diastereomer , enantiomer , crown ether , chemistry , ether , enantiomeric excess , organic chemistry , chromatography , hydrolysis , adsorption , enantioselective synthesis , catalysis , ion
The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate the racemic mixture of L-alanine ether of phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due to the formation of complexes of different stability between diastereomers and optically selective adsorbents on a host-guest principle. The separated diastereomers were converted into enantiomers by hydrolysis. The structure and optical activity of the synthesized crown ether and separated enantiomers were investigated by physicochemical methods