Open AccessEquianalgesic Oxycodone, Continuous Intravenous Morphine in Post- Long Bone Surgery
Author(s) -
Franz Josef Tarigan,
Achsanuddin Hanafie,
Hasanul Arifin,
Dadik Wahyu Wijaya
Publication year - 2019
Publication title -
sumatera medical journal
Language(s) - English
Resource type - Journals
eISSN - 2622-9234
pISSN - 2622-1357
DOI - 10.32734/sumej.v2i3.1240
Subject(s) - oxycodone , morphine , medicine , anesthesia , analgesic , orthopedic surgery , surgery , opioid , receptor
Oxycodone and morphine are powerful analgesic drugs used for post-operative pain management. There is no studies have been conducted to assess the dose equivalency between the two drugs. To get an equianalgesic dose of Oxycodone and Morphine. This study was using a double-blind randomized clinical trials, 48 samples, ages 21-60 years, PS ASA I-II, which will get an elective orthopedic surgery using general anesthesia tech-niques. Oxycodone (group A) : Morphine (group B) (Initial 5mg than continuous 1 mg/hour : initial dose 4mg than continuous 0,5 mg/hour). Average drug dose for group that takes morphine and oxycodone (3.90 ± 0.46 mg : 1.46 ± 0.51 mg). No significant difference between the average dose (p <0.05). Equianalgesic dosein group Oxycodone and Morphine is 1.4 mg: 3.9mg.