Open AccessAPPLICATION OF GLASS IONOMER CEMENT (GIC) FOR REPAIRING DENTAL PULP BY MEASURING EXPRESSION OF DENTIN MATRIX PROTEIN-1
Author(s) -
Endang Suprastiwi,
Siti Mardewi Soerono Akbar,
Narlan Sumawinata,
Ellyza Herda
Publication year - 2013
Publication title -
dentika
Language(s) - English
Resource type - Journals
eISSN - 2615-854X
pISSN - 1693-671X
DOI - 10.32734/dentika.v17i4.1777
Subject(s) - glass ionomer cement , pulp (tooth) , dentin , dentistry , cement , chemistry , materials science , composite material , medicine
Glass ionomer cement (GIC) has a potential to improve the pulp by inducing Dentin Matrix Protein-1 (DMP-1) release that can mineralize dentin. This study used three types of glass ionomer cements; Conventional GIC i.e. GC Fuji IX; resin-modified glass ionomer cement (RMGIC) i.e. GC Fuji II LC and Nano particle of RMGIC i.e. Ketac™ N100 3MEspe. The three materials were applied to the tooth pulp of Macaca nemestrina. Expression of DMP-1 extract-dental pulp of the subjects was investigated by using ELISA. This study was statistically analyzed by using Mann-Whitney test. The result showed that GICs has a potential to induce the expression of DMP-1 and there was no significant differences among the three groups of GIC to induce DMP-1(p≥ 0,05). In conclucion, all tested materials have a potential in dental pulp repair by expressing DMP-1.