Open AccessHubungan status nutrisi penderita karsinoma nasofaring stadium lanjut dengan kejadian mukositis sesudah radioterapi
Author(s) -
Fransiska Tricia,
Pudji Rahaju,
Rus Suheryanto
Publication year - 2012
Publication title -
oto rhino laryngologica indonesiana/oto-rhino-laryngologica indonesiana
Language(s) - English
Resource type - Journals
eISSN - 0216-3667
pISSN - 2598-3970
DOI - 10.32637/orli.v42i1.40
Subject(s) - mucositis , medicine , transferrin , radiation therapy , gastroenterology , albumin , wilcoxon signed rank test , body mass index , mann–whitney u test
Background: Normal nutritional status is a balanced condition of nutritional intake and requirement in a person. Lack of nutrition in cancer patients promotes undesirable effects on various organs and systems of the body. Purpose: To determine the nutritional status differences in patients with advanced stage NPC type III WHO before and after radiotherapy, and the relationship between nutritional status with mucositis occurance after radiotherapy. Method: Observational analytic study. Sampling was conducted by non-random purposive sampling technique with 10 subjects with NPC. The statistical analysis used paired sample Wilcoxon test and Spearman correlation test. Result: The study found significant differences between nutritional state regarding BMI, LOLA and transferrin before and after radiotherapy with p 0,05). Uji korelasi hubungan antara BMI, LOLA, albumin, dan transferinsesudah radioterapi menunjukkan bahwa status nutrisi tidak berhubungan secara signifikan dengan kejadian mukositis sesudah radioterapi (BMI p=0,122, LOLA p=0,209, albumin p=0,902 dan transferin p=1,000 dengan p>0,05) Kesimpulan: Pemberian radioterapi pada penderita KNF stadium lanjut menyebabkan penurunan bermakna pada status nutrisi sebelum dan sesudah radioterapi, tetapi tidak berhubungan secara bermakna dengan kejadian mukositis sesudah radioterapi. Kata kunci: karsinoma nasofaring, radioterapi, status nutrisi, malnutrisi, mukositis.