Open AccessHepatoprotective Effects of Camel Milk and Urine on Carbon Tetrachloride (CCL4) induced Liver Damage
Author(s) -
Khan Rawoof,
Hussien Mohamed,
Gouman Ali
Publication year - 2019
Publication title -
international journal of scientific research in science, engineering and technology
Language(s) - English
Resource type - Journals
eISSN - 2395-1990
pISSN - 2394-4099
DOI - 10.32628/ijsrset196169
Subject(s) - carbon tetrachloride , ccl4 , urine , liver damage , chemistry , liver injury , pharmacology , medicine , biochemistry , organic chemistry
Carbon tetrachloride (CCL4) is a highly toxic chemical agent and is the most commonly used drug to experimentally induce liver damage. Aim of the study the aim is to investigate the possible protective role of both camel milk and urine on CCL4 induced liver damage. Method 20 rates were used in the study and they were classified into 4 different groups. Group I control, Group II CCL4 group, Group III (milk+CCL4), Group IV (urine+ CCL4). Biochemical parameters in addition to liver enzymes were estimated to evaluated the liver damage. Results the CCl4 treatment markedly affected the liver-specific enzyme activities. A significant (P < 0.05) increase in serum AST (135± 13.6 IU/L), ALT (157± 24.3 IU/L), and ALP (1209 ± 2.59 IU/L) activities was observed in the CCl4-treated rats compared with those of the control rats (104 ± 6.9 IU/L, 101±14.6 IU/L, 146.8±11.2 IU/L) respectively. Concluded from this study that Camel urine has protective effect against CCL4 induced liver damage more than Camel milk.