Open AccessThe Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
Author(s) -
Fateme Abdolahzade-Arani,
Farzad Kahrizi,
Amir Ghaderi,
Hamid Reza Banafsheh
Publication year - 2021
Publication title -
international journal of medical toxicology and forensic medicine
Language(s) - English
Resource type - Journals
eISSN - 2251-8770
pISSN - 2251-8762
DOI - 10.32598/ijmtfm.v11i3.34968
Subject(s) - medicine , depression (economics) , vitamin d and neurology , anxiety , beck depression inventory , beck anxiety inventory , methadone maintenance , hypovitaminosis , methadone , vitamin , bone mineral , vitamin d deficiency , gastroenterology , psychiatry , osteoporosis , economics , macroeconomics
Background: Hypovitaminosis D, low bone mineral density, non-specific musculoskeletal pain, increased risk of fracture, and periodontal disease were reported in most subjects recruited from the Methadone Maintenance Treatment (MMT) program. This study aimed to determine the relationship between vitamin D levels and the severity of anxiety and depression in patients under MMT. Methods: In a cross-sectional study, serum vitamin D levels were measured among 500 patients under MMT from Kashan Province, Iran. Correlation tests were used to assess the association of vitamin D levels with the severity of anxiety and depression in the explored patients. Results: We found that serum vitamin D levels were positively correlated with the scores of the Beck Depression Inventory (BDI) (r=0.107, P=0.017) and the Beck Anxiety Inventory (BAI) (r=0.129, P=0.004). Additionally, there was a negative correlation between serum vitamin D levels, MMT dosage (r=-0.011, P=0.8), and the duration of MMT (r=-0.017, P=0.7). Conclusion: Our findings demonstrated that serum vitamin D levels were independently correlated with the BDI and BAI scores. Further studies are required to confirm our findings.