The Synthesis and Evaluation of anti-tubercular activity for some new 4-{4-[(hydrazinylmethoxy) (hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one novel Derivatives. | Zendy

Shripad Potadar | Zendy; Ramling Kotnal | Zendy

Open Access

The Synthesis and Evaluation of anti-tubercular activity for some new 4-{4-[(hydrazinylmethoxy) (hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one novel Derivatives.

Author(s) -

Shripad Potadar,

Ramling Kotnal

Publication year - 2020

Publication title -

journal of biomedical and pharmaceutical research

Language(s) - English

Resource type - Journals

eISSN - 2589-8752

pISSN - 2279-0594

DOI - 10.32553/jbpr.v8i6.703

Subject(s) - quinoxaline , chemistry , proton nmr , elemental analysis , spectral analysis , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , spectroscopy , physics , quantum mechanics

A new series of 4-{4-[(hydrazinylmethoxy)(hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one were designed and synthesized in order to evaluate their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities. Keywords: Quinoxaline, ortho-phenylenediamine and hydrazinehydrate.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research