Open AccessManagement of Peripheral Neuropathy and Cardiovascular Effects in Vitamin B12 Deficiency
Author(s) -
Nishant Kumar Singh,
Hirni J Patel,
Mohit Buddhadev,
S P Srinivas Nayak,
G. S. Chakraborthy
Publication year - 2021
Publication title -
journal of biomedical and pharmaceutical research
Language(s) - English
Resource type - Journals
eISSN - 2589-8752
pISSN - 2279-0594
DOI - 10.32553/jbpr.v10i5.884
Subject(s) - medicine , hyperhomocysteinemia , peripheral neuropathy , vitamin b12 , homocysteine , etiology , disease , peripheral , b vitamins , cobalamin , coronary artery disease , arterial disease , vascular disease , gastroenterology , endocrinology , diabetes mellitus
Peripheral nerves are susceptible to damage by a wide array of toxins, medications, and vitamin deficiencies. Vitamin B12 (VB12) deficiency neuropathy is a rare debilitating disease that affects mostly the elderly. It is important to consider these etiologies when approaching patients with a variety of neuropathic presentations in this review were have included most relevant and latest information on mechanisms causing Peripheral neuropathy in VB12 deficiency. We also have included cardiovascular disorders and their management. Hyperhomocysteinemia has been implicated in endothelial dysfunction and cardiovascular disease. The association of homocysteine (Hcy) and VB12 with cardiovascular risk factors in patients with coronary artery disease (CAD) has also been studied
Keywords: Peripheral Neuropathy, Vitamin B12 Deficiency, Cardiovascular Disease and Homocysteine.